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Article Name Alkaloid Biosynthesis Mechanism in Opium Poppy (Papaver somniferum L.)
Author Name Tuğba GÜRKÖK, İskender PARMAKSIZ*, Gülşen BOZTEPE, Elif KAYMAK
Address Gaziosmanpaşa Üniversitesi, Fen Edebiyat Fak, Biyoloji Bölümü, Tokat
Abstract Alkaloids include nitrogen atom(s) in their molecular structure and found in alkali form in plants. Alkaloids have potent pharmacological and toxicity effects. Plants are estimated to produce approximately 12.000 different alkaloids. Alkaloid biosynthesis in plants involves many catalytic steps that are catalyzed by a number of enzymes belong to a wide range of protein families. The opium poppy, Papaver somniferum L., produces several types of benzylisoquinoline alkaloids including the narcotic analgesic morphine, the cough suppressant codeine, the muscle relaxant papaverine, and the anti-microbial agents such as sanguinarine and berberine. This plant is mostly used to investigate to elucidate the mechanism of alkaloid biosynthesis and pathways. In recent years, there has been a lot of study both on the biochemical structure and functions of enzymes involved in alkaloid biosynthesis and also on biotechnological applications. This study was carried out to present the known biosynthetic pathways of alkaloids in opium poppy, Papaver somniferum L.).
Published in Electronic Journal of BioTechnology
Issue 1
Volume 2
Pages 31-46
Year 2010
Type Review
Language Turkish
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